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FoxO1 Overexpression Ameliorates TNF-α-Induced Oxidative Damage and Promotes Osteogenesis of Human Periodontal Ligament Stem Cells via Antioxidant Defense Activation

Periodontitis is a chronic disease that includes the pathologic loss of periodontal tissue and alveolar bone. The inflammatory environment in periodontitis impairs the osteogenic differentiation potential and depresses the regeneration capacity of human periodontal ligament stem cells (hPDLSCs). Sin...

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Detalles Bibliográficos
Publicado en:Stem Cells Int
Main Authors: Huang, Xiaojun, Chen, Huan, Xie, Yunyi, Cao, Zeyuan, Lin, Xuefeng, Wang, Yan
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6875375/
https://ncbi.nlm.nih.gov/pubmed/31781234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/2120453
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