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FoxO1 Overexpression Ameliorates TNF-α-Induced Oxidative Damage and Promotes Osteogenesis of Human Periodontal Ligament Stem Cells via Antioxidant Defense Activation

Periodontitis is a chronic disease that includes the pathologic loss of periodontal tissue and alveolar bone. The inflammatory environment in periodontitis impairs the osteogenic differentiation potential and depresses the regeneration capacity of human periodontal ligament stem cells (hPDLSCs). Sin...

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Dades bibliogràfiques
Publicat a:Stem Cells Int
Autors principals: Huang, Xiaojun, Chen, Huan, Xie, Yunyi, Cao, Zeyuan, Lin, Xuefeng, Wang, Yan
Format: Artigo
Idioma:Inglês
Publicat: Hindawi 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6875375/
https://ncbi.nlm.nih.gov/pubmed/31781234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/2120453
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