Overexpression of the FoxO1 Ameliorates Mesangial Cell Dysfunction in Male Diabetic Rats

The dysfunction of mesangial cells (MCs) in high-glucose (HG) conditions plays pivotal role in inducing glomerular sclerosis by causing the imbalance between generation and degradation of extracellular matrix (ECM) proteins, which ultimately leads to diabetic nephropathy. This study was designed to...

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Detalhes bibliográficos
Publicado no:Mol Endocrinol
Main Authors: Qin, Guijun, Zhou, Yingni, Guo, Feng, Ren, Lei, Wu, Lina, Zhang, Yuanyuan, Ma, Xiaojun, Wang, Qingzhu
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2015
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5414709/
https://ncbi.nlm.nih.gov/pubmed/26029993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2014-1372
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