Inhibition of cAMP/PKA Pathway Protects Optic Nerve Head Astrocytes against Oxidative Stress by Akt/Bax Phosphorylation-Mediated Mfn1/2 Oligomerization

Glaucoma is characterized by a progressive optic nerve degeneration and retinal ganglion cell loss, but the underlying biological basis for the accompanying neurodegeneration is not known. Accumulating evidence indicates that structural and functional abnormalities of astrocytes within the optic ner...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Oxid Med Cell Longev
Autori principali: Ju, Won-Kyu, Shim, Myoung Sup, Kim, Keun-Young, Park, Tae Lim, Ahn, Sangphil, Edwards, Genea, Weinreb, Robert N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi 2019
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6875302/
https://ncbi.nlm.nih.gov/pubmed/31781352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/8060962
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi