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Expedited mapping of the ligandable proteome using fully functionalized enantiomeric probe pairs
A fundamental challenge in chemical biology and medicine is to understand and expand the fraction of the human proteome that can be targeted by small molecules. We recently described a strategy that integrates fragment-based ligand discovery with chemical proteomics to furnish global portraits of re...
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| Veröffentlicht in: | Nat Chem |
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| Hauptverfasser: | , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6874898/ https://ncbi.nlm.nih.gov/pubmed/31659311 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41557-019-0351-5 |
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