The phosphorylation status of Ser-637 in dynamin-related protein 1 (Drp1) does not determine Drp1 recruitment to mitochondria

Recruitment of the GTPase dynamin-related protein 1 (Drp1) to mitochondria is a central step required for mitochondrial fission. Reversible Drp1 phosphorylation has been implicated in the regulation of this process, but whether Drp1 phosphorylation at Ser-637 determines its subcellular localization...

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Vydáno v:J Biol Chem
Hlavní autoři: Yu, Rong, Liu, Tong, Ning, Chenfei, Tan, Fei, Jin, Shao-Bo, Lendahl, Urban, Zhao, Jian, Nistér, Monica
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2019
Témata:
Cell Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6873174/
https://ncbi.nlm.nih.gov/pubmed/31533986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.008202
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