Human MIEF1 recruits Drp1 to mitochondrial outer membranes and promotes mitochondrial fusion rather than fission

Mitochondrial morphology is controlled by two opposing processes: fusion and fission. Drp1 (dynamin-related protein 1) and hFis1 are two key players of mitochondrial fission, but how Drp1 is recruited to mitochondria and how Drp1-mediated mitochondrial fission is regulated in mammals is poorly under...

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Detalhes bibliográficos
Main Authors: Zhao, Jian, Liu, Tong, Jin, Shaobo, Wang, Xinming, Qu, Mingqi, Uhlén, Per, Tomilin, Nikolay, Shupliakov, Oleg, Lendahl, Urban, Nistér, Monica
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3160255/
https://ncbi.nlm.nih.gov/pubmed/21701560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.198
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