Genome Wide Analysis Approach Suggests Chromosome 2 Locus to be Associated with Thiazide and Thiazide Like-Diuretics Blood Pressure Response

Chlorthalidone (CTD) is more potent than hydrochlorothiazide (HCTZ) in reducing blood pressure (BP) in hypertensive patients, though both are plagued with BP response variability. However, there is a void in the literature regarding the genetic determinants contributing to the variability observed i...

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Опубликовано в: :Sci Rep
Главные авторы: Singh, Sonal, McDonough, Caitrin W., Gong, Yan, Bailey, Kent R., Boerwinkle, Eric, Chapman, Arlene B., Gums, John G., Turner, Stephen T., Cooper-DeHoff, Rhonda M., Johnson, Julie A.
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2019
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6872535/
https://ncbi.nlm.nih.gov/pubmed/31754133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-53345-5
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