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Whole Transcriptome Sequencing Analyses Reveal Molecular Markers of Blood Pressure Response to Thiazide Diuretics

Thiazide diuretics (TD) are commonly prescribed anti-hypertensives worldwide. However, <40% of patients treated with thiazide monotherapy achieve BP control. This study uses whole transcriptome sequencing to identify novel molecular markers associated with BP response to TD. We assessed global RN...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Sá, Ana Caroline C., Webb, Amy, Gong, Yan, McDonough, Caitrin W., Datta, Somnath, Langaee, Taimour Y., Turner, Stephen T., Beitelshees, Amber L., Chapman, Arlene B., Boerwinkle, Eric, Gums, John G., Scherer, Steven E., Cooper-DeHoff, Rhonda M., Sadee, Wolfgang, Johnson, Julie A.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5700078/
https://ncbi.nlm.nih.gov/pubmed/29167564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16343-z
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