Association of variants in NEDD4L with blood pressure response and adverse cardiovascular outcomes in hypertensive patients treated with thiazide diuretics

OBJECTIVE: Single-nucleotide polymorphisms (SNPs) in NEDD4L may influence the ability of the NEDD4L protein to reduce epithelial sodium channel expression. A variant in NEDD4L, rs4149601, was associated with antihypertensive response and cardiovascular outcomes during treatment with thiazide diureti...

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Detalhes bibliográficos
Main Authors: McDonough, Caitrin W., Burbage, Sarah E., Duarte, Julio D., Gong, Yan, Langaee, Taimour Y., Turner, Stephen T., Gums, John G., Chapman, Arlene B., Bailey, Kent R., Beitelshees, Amber L., Boerwinkle, Eric, Pepine, Carl J., Cooper-DeHoff, Rhonda M., Johnson, Julie A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3756535/
https://ncbi.nlm.nih.gov/pubmed/23353631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/HJH.0b013e32835e2a71
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