The Reversal Effect of Sigma-1 Receptor (S1R) Agonist, SA4503, on Atrial Fibrillation After Depression and Its Underlying Mechanism

AIM: Sigma-1 receptors have been investigated and shown to play a protective role in both depression and cardiovascular disease. SA4503, known as a σ1 receptor agonist, regulates cardiac calcium and potassium channels in rat models of depression. However, it remains unknown whether SA4503 can allevi...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Liu, Xin, Qu, Chuan, Shi, Shaobo, Ye, Tianxin, Wang, Linglin, Liu, Steven, Zhang, Cui, Liang, Jinjun, Hu, Dan, Yang, Bo
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6870537/
https://ncbi.nlm.nih.gov/pubmed/31803058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2019.01346
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