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SUMO3 modification by PIAS1 modulates androgen receptor cellular distribution and stability
BACKGROUND: Abnormal reactivation of androgen receptor (AR) signaling in castration-resistant prostate cancer (CRPC) mainly results from overexpression and down-regulation of AR. Sumoylation of AR can influence its function. However, regulation of AR sumoylation by SUMO E3 ligases PIASs to modify AR...
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| Publicado no: | Cell Commun Signal |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6868827/ https://ncbi.nlm.nih.gov/pubmed/31752909 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-019-0457-9 |
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