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Butyrophilin-like 3 Directly Binds a Human Vγ4(+) T Cell Receptor Using a Modality Distinct from Clonally-Restricted Antigen
Butyrophilin (BTN) and butyrophilin-like (BTNL/Btnl) heteromers are major regulators of human and mouse γδ T cell subsets, but considerable contention surrounds whether they represent direct γδ T cell receptor (TCR) ligands. We demonstrate that the BTNL3 IgV domain binds directly and specifically to...
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| Publicat a: | Immunity |
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| Autors principals: | , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cell Press
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6868513/ https://ncbi.nlm.nih.gov/pubmed/31628053 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2019.09.006 |
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