The human Vδ2(+) T-cell compartment comprises distinct innate-like Vγ9(+) and adaptive Vγ9(-) subsets

Vδ2(+) T cells form the predominant human γδ T-cell population in peripheral blood and mediate T-cell receptor (TCR)-dependent anti-microbial and anti-tumour immunity. Here we show that the Vδ2(+) compartment comprises both innate-like and adaptive subsets. Vγ9(+) Vδ2(+) T cells display semi-invaria...

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Udgivet i:Nat Commun
Main Authors: Davey, Martin S., Willcox, Carrie R., Hunter, Stuart, Kasatskaya, Sofya A., Remmerswaal, Ester B. M., Salim, Mahboob, Mohammed, Fiyaz, Bemelman, Frederike J., Chudakov, Dmitriy M., Oo, Ye H., Willcox, Benjamin E.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5932074/
https://ncbi.nlm.nih.gov/pubmed/29720665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04076-0
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