Clostridium perfringens epsilon toxin induces blood brain barrier permeability via caveolae-dependent transcytosis and requires expression of MAL

Clostridium perfringens epsilon toxin (ETX) is responsible for causing the economically devastating disease, enterotoxaemia, in livestock. It is well accepted that ETX causes blood brain barrier (BBB) permeability, however the mechanisms involved in this process are not well understood. Using in viv...

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Vydáno v:PLoS Pathog
Hlavní autoři: Linden, Jennifer R., Flores, Claudia, Schmidt, Eric F., Uzal, Francisco A., Michel, Adam O., Valenzuela, Marissa, Dobrow, Sebastian, Vartanian, Timothy
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2019
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6867657/
https://ncbi.nlm.nih.gov/pubmed/31703116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008014
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