Clostridium perfringens Epsilon Toxin Compromises the Blood-Brain Barrier in a Humanized Zebrafish Model

Clostridium perfringens epsilon toxin (ETX) is hypothesized to mediate blood-brain barrier (BBB) permeability by binding to the myelin and lymphocyte protein (MAL) on the luminal surface of endothelial cells (ECs). However, the kinetics of this interaction and a general understanding of ETX's b...

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Udgivet i:iScience
Main Authors: Adler, Drew, Linden, Jennifer R., Shetty, Samantha V., Ma, Yinghua, Bokori-Brown, Monika, Titball, Richard W., Vartanian, Timothy
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6487375/
https://ncbi.nlm.nih.gov/pubmed/31030181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2019.04.016
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