Clostridium perfringens epsilon toxin induces blood brain barrier permeability via caveolae-dependent transcytosis and requires expression of MAL

Clostridium perfringens epsilon toxin (ETX) is responsible for causing the economically devastating disease, enterotoxaemia, in livestock. It is well accepted that ETX causes blood brain barrier (BBB) permeability, however the mechanisms involved in this process are not well understood. Using in viv...

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Bibliografiska uppgifter
I publikationen:PLoS Pathog
Huvudupphovsmän: Linden, Jennifer R., Flores, Claudia, Schmidt, Eric F., Uzal, Francisco A., Michel, Adam O., Valenzuela, Marissa, Dobrow, Sebastian, Vartanian, Timothy
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2019
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6867657/
https://ncbi.nlm.nih.gov/pubmed/31703116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008014
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