Synthesis and Antiplasmodial Activity of 1,2,3-Triazole-Naphthoquinone Conjugates

A series of 34 1,2,3-triazole-naphthoquinone conjugates were synthesized via copper-catalyzed cycloaddition (CuAAC). They were evaluated for their in vitro antimalarial activity against chloroquine-sensitive strains of Plasmodium falciparum and against three different tumor cell lines (SKBr-3, MCF-7...

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Bibliographic Details
Published in:Molecules
Main Authors: Oramas-Royo, Sandra, López-Rojas, Priscila, Amesty, Ángel, Gutiérrez, David, Flores, Ninoska, Martín-Rodríguez, Patricia, Fernández-Pérez, Leandro, Estévez-Braun, Ana
Format: Artigo
Language:Inglês
Published: MDPI 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6864696/
https://ncbi.nlm.nih.gov/pubmed/31671684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24213917
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