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1,2,3-Triazole β-lactam conjugates as antimicrobial agents

A convenient and efficient synthesis of new triazole β-lactam conjugates using click chemistry is described. β-lactam 15 and 16 were prepared using cycloaddition strategy and propargylated at N-1 to afford compounds 17 and 18. Cu-catalyzed click reaction of these β-lactams 17 and 18 with different a...

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Detalhes bibliográficos
Publicado no:Heliyon
Main Authors: Kaur, Rajneesh, Singh, Raman, Kumar, Antresh, Kaur, Satvinder, Priyadarshi, Nitesh, Singhal, Nitin Kumar, Singh, Kuldeep
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7327255/
https://ncbi.nlm.nih.gov/pubmed/32637684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2020.e04241
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