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Anesthetic Agents Isoflurane and Propofol Decrease Maximal Ca(2+)-Activated Force and Thus Contractility in the Failing Myocardium
In the normal heart, frequently used anesthetics such as isoflurane and propofol can reduce inotropy. However, the impact of these agents on the failing myocardium is unclear. Here, we examined whether and how isoflurane and propofol influence cardiac contractility in intact cardiac muscles from rat...
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| Udgivet i: | J Pharmacol Exp Ther |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The American Society for Pharmacology and Experimental Therapeutics
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6863458/ https://ncbi.nlm.nih.gov/pubmed/31515443 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.119.259556 |
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