Antibiotic resistance and inhibition mechanism of novel aminoglycoside phosphotransferase APH(5) from B. subtilis subsp. subtilis strain RK

Bacterial resistance towards aminoglycoside antibiotics mainly occurs because of aminoglycoside phosphotransferases (APHs). It is thus necessary to provide a rationale for focusing inhibitor development against APHs. The nucleotide triphosphate (NTP) binding site of eukaryotic protein kinases (ePKs)...

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Detalhes bibliográficos
Publicado no:Braz J Microbiol
Main Authors: Parulekar, Rishikesh S., Barale, Sagar S., Sonawane, Kailas D.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2019
Assuntos:
Bacterial and Fungal Pathogenesis - Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6863407/
https://ncbi.nlm.nih.gov/pubmed/31401782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s42770-019-00132-z
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