Adenovirus Vector-Based Vaccines Confer Maternal-Fetal Protection Against Zika Virus Challenge in Pregnant IFNαR(−/−) Mice

Maternal infection with Zika virus (ZIKV) can lead to microcephaly and other congenital abnormalities of the fetus. Although ZIKV vaccines that prevent or reduce viremia in non-pregnant mice have been described, a maternal vaccine that provides complete fetal protection would be desirable. Here we s...

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Detalhes bibliográficos
Publicado no:Cell Host Microbe
Main Authors: Larocca, Rafael A., Mendes, Erica A., Abbink, Peter, Peterson, Rebecca L., Martinot, Amanda J., Iampietro, M. Justin, Kang, Zi H., Aid, Malika, Kirilova, Marinela, Jacob-Dolan, Catherine, Tostanoski, Lisa, Borducchi, Erica N., De La Barrera, Rafael A., Barouch, Dan H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6863051/
https://ncbi.nlm.nih.gov/pubmed/31668877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2019.10.001
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