Therapeutic and Protective Efficacy of a Dengue Antibody Against Zika Infection in Rhesus Monkeys

Strategies to treat Zika virus (ZIKV) infection in dengue virus (DENV) endemic areas are urgently needed. Here we show that a DENV-specific antibody against the E-dimer epitope (EDE) potently cross-neutralizes ZIKV and provides robust therapeutic efficacy as well as prophylactic efficacy against ZIK...

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Bibliographic Details
Published in:Nat Med
Main Authors: Abbink, Peter, Larocca, Rafael A., Dejnirattisai, Wanwisa, Peterson, Rebecca, Nkolola, Joseph P., Borducchi, Erica N., Supasa, Piyada, Mongkolsapaya, Juthathip, Screaton, Gavin R., Barouch, Dan H.
Format: Artigo
Language:Inglês
Published: 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5992501/
https://ncbi.nlm.nih.gov/pubmed/29867228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41591-018-0056-0
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