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Anti-Dengue E-dimer epitope human antibodies have therapeutic activity against Zika virus infection
The Zika virus (ZIKV) epidemic has resulted in congenital abnormalities in fetuses and neonates. Although some cross-reactive DENV antibodies can enhance ZIKV infection in mice, those recognizing the E-dimer epitope (EDE) can neutralize ZIKV infection in cell culture. We evaluated the therapeutic ac...
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| Yayımlandı: | Nat Immunol |
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| Asıl Yazarlar: | , , , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2017
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5679314/ https://ncbi.nlm.nih.gov/pubmed/28945244 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3849 |
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