Implications of Immune Checkpoint Expression During Aging in HIV-Infected People on Antiretroviral Therapy

Immune checkpoint molecules (ICMs) regulate T cell responses. In chronic viral infections and cancer, where antigens can persistently stimulate the immune system, ICMs can serve as a barrier to effective immune responses. The role of ICMs in the setting of systemic low-grade inflammation as in aging...

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Vydáno v:AIDS Res Hum Retroviruses
Hlavní autoři: de Armas, Lesley R., Pallikkuth, Suresh, Rinaldi, Stefano, Pahwa, Rajendra, Pahwa, Savita
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc., publishers 2019
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6862963/
https://ncbi.nlm.nih.gov/pubmed/31578868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2019.0135
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