Single Cell Profiling Reveals PTEN Overexpression in Influenza-Specific B cells in Aging HIV-infected individuals on Anti-retroviral Therapy

Memory B cells (MBC) respond to secondary antigen challenge to protect against infection and to boost immunity following vaccinations. Despite effective treatment, chronic HIV infection disturbs MBCs by reducing numbers and altering functionality due to hyper-activation and increased apoptosis leadi...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: de Armas, Lesley R., Pallikkuth, Suresh, Pan, Li, Rinaldi, Stefano, Cotugno, Nicola, Andrews, Sarah, Pahwa, Rajendra, McDermott, Adrian B., Palma, Paolo, Pahwa, Savita
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2019
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6385500/
https://ncbi.nlm.nih.gov/pubmed/30792481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-38906-y
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