Single Cell Profiling Reveals PTEN Overexpression in Influenza-Specific B cells in Aging HIV-infected individuals on Anti-retroviral Therapy

Memory B cells (MBC) respond to secondary antigen challenge to protect against infection and to boost immunity following vaccinations. Despite effective treatment, chronic HIV infection disturbs MBCs by reducing numbers and altering functionality due to hyper-activation and increased apoptosis leadi...

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Опубликовано в: :Sci Rep
Главные авторы: de Armas, Lesley R., Pallikkuth, Suresh, Pan, Li, Rinaldi, Stefano, Cotugno, Nicola, Andrews, Sarah, Pahwa, Rajendra, McDermott, Adrian B., Palma, Paolo, Pahwa, Savita
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2019
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6385500/
https://ncbi.nlm.nih.gov/pubmed/30792481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-38906-y
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