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Exosome release and neuropathology induced by α-synuclein: new insights into protective mechanisms of Drp1 inhibition

Targeting alpha-synuclein (α-syn) as a therapeutic strategy for Parkinson’s disease (PD) has been intensively pursued largely due to its well-recognized pathogenic role. Since its discovery as the first familial link to PD over two decades ago, this protein has been associated with multiple neurotox...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol Commun
Main Authors: Fan, Rebecca Z., Guo, Min, Luo, Shouqing, Cui, Mei, Tieu, Kim
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6862865/
https://ncbi.nlm.nih.gov/pubmed/31744532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-019-0821-4
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