Drp1 inhibition attenuates neurotoxicity and dopamine release deficits in vivo

Mitochondrial dysfunction has been reported in both familial and sporadic Parkinson’s disease (PD). However, effective therapy targeting this pathway is currently inadequate. Recent studies suggest that manipulating the processes of mitochondrial fission and fusion has considerable potential for tre...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Rappold, Phillip M., Cui, Mei, Grima, Jonathan C., Fan, Rebecca Z., de Mesy-Bentley, Karen L., Chen, Linan, Zhuang, Xiaoxi, Bowers, William J., Tieu, Kim
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223875/
https://ncbi.nlm.nih.gov/pubmed/25370169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6244
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