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A Crucial Role for the Small GTPase Rac1 Downstream of the Protein Kinase Akt2 in Insulin Signaling that Regulates Glucose Uptake in Mouse Adipocytes

Insulin-stimulated glucose uptake is mediated by translocation of the glucose transporter GLUT4 to the plasma membrane in adipocytes and skeletal muscle cells. In both types of cells, phosphoinositide 3-kinase and the protein kinase Akt2 have been implicated as critical regulators. In skeletal muscl...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Takenaka, Nobuyuki, Nakao, Mika, Matsui, Sayaka, Satoh, Takaya
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6861951/
https://ncbi.nlm.nih.gov/pubmed/31683681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20215443
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