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Involvement of the protein kinase Akt2 in insulin-stimulated Rac1 activation leading to glucose uptake in mouse skeletal muscle

Translocation of the glucose transporter GLUT4 to the sarcolemma accounts for glucose uptake in skeletal muscle following insulin administration. The protein kinase Akt2 and the small GTPase Rac1 have been implicated as essential regulators of insulin-stimulated GLUT4 translocation. Several lines of...

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Vydáno v:PLoS One
Hlavní autoři: Takenaka, Nobuyuki, Araki, Natsumi, Satoh, Takaya
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6368313/
https://ncbi.nlm.nih.gov/pubmed/30735546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0212219
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