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Crucial role of the small GTPase Rac1 in insulin-stimulated translocation of glucose transporter 4 to the mouse skeletal muscle sarcolemma

The Rho family GTPase Rac1 has been implicated in the regulation of glucose uptake in myoblast cell lines. However, no evidence for the role of Rac1 has been provided by a mouse model. The purpose of this study is to test the involvement of Rac1 in insulin action in mouse skeletal muscle. Intravenou...

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Hlavní autoři: Ueda, Shuji, Kitazawa, Sohei, Ishida, Kota, Nishikawa, Yuki, Matsui, Megumi, Matsumoto, Hikaru, Aoki, Takuji, Nozaki, Shinsuke, Takeda, Tomoya, Tamori, Yoshikazu, Aiba, Atsu, Kahn, C. Ronald, Kataoka, Tohru, Satoh, Takaya
Médium: Artigo
Jazyk:Inglês
Vydáno: Federation of American Societies for Experimental Biology 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183928/
https://ncbi.nlm.nih.gov/pubmed/20203090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.09-137380
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