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TDP-43 inhibitory peptide alleviates neurodegeneration and memory loss in an APP transgenic mouse model for Alzheimer’s disease

Alzheimer's disease (AD) is the leading cause of dementia in the elderly, characterized clinically by progressive decline in cognitive function and neuropathologically by the presence of senile plaques and neuronal loss in the brain. While current drugs for AD are always employed as symptomatic...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta Mol Basis Dis
Principais autores: Gao, Ju, Wang, Luwen, Gao, Chao, Arakawa, Hiroyuki, Perry, George, Wang, Xinglong
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6861700/
https://ncbi.nlm.nih.gov/pubmed/31678156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2019.165580
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