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Association Between TDP-43 and Mitochondria in Inclusion Body Myositis

Inclusion body myositis (IBM) is the most common cause of primary myopathy in individuals ages 50 years and over, and is pathologically characterized by protein aggregates of p62 and mislocalized cytoplasmic TDP-43 as well as mitochondrial abnormalities in affected muscle fibers. Our recent studies...

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Podrobná bibliografie
Vydáno v:Lab Invest
Hlavní autoři: Huntley, Mikayla L., Gao, Ju, Termsarasab, Pichet, Wang, Luwen, Zeng, Sophia, Thammongkolchai, Thananan, Liu, Ying, Cohen, Mark L., Wang, Xinglong
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6609472/
https://ncbi.nlm.nih.gov/pubmed/30742062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41374-019-0233-x
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