Association Between TDP-43 and Mitochondria in Inclusion Body Myositis

Inclusion body myositis (IBM) is the most common cause of primary myopathy in individuals ages 50 years and over, and is pathologically characterized by protein aggregates of p62 and mislocalized cytoplasmic TDP-43 as well as mitochondrial abnormalities in affected muscle fibers. Our recent studies...

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Udgivet i:Lab Invest
Main Authors: Huntley, Mikayla L., Gao, Ju, Termsarasab, Pichet, Wang, Luwen, Zeng, Sophia, Thammongkolchai, Thananan, Liu, Ying, Cohen, Mark L., Wang, Xinglong
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6609472/
https://ncbi.nlm.nih.gov/pubmed/30742062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41374-019-0233-x
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