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TDP-43 proteinopathy and mitochondrial abnormalities in neurodegeneration
Genetic mutations in TAR DNA-binding protein 43 (TDP-43) cause amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Importantly, TDP-43 proteinopathy, characterized by aberrant phosphorylation, ubiquitination, cleavage or nuclear depletion of TDP-43 in neurons and glial cells, is a...
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| Publicado no: | Mol Cell Neurosci |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6874890/ https://ncbi.nlm.nih.gov/pubmed/31445085 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2019.103396 |
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