Mimetic sHDL Nanoparticles: a Novel Drug-Delivery Strategy to Target Triple-Negative Breast Cancer

INTRODUCTION: Withanolides are naturally-derived HSP90 inhibitors that are potent in preclinical models of triple negative breast cancers (TNBC). Conjugation to synthetic. high-density lipoprotein (sHDL) nanoparticles improves solubility and targets delivery to the scavenger receptor B1 (SR-B1). TNB...

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Detalhes bibliográficos
Publicado no:Surgery
Main Authors: Wang, T, Subramanian, C, Yu, M, White, P, Kuai, R, Sanchez, J, Moon, J, Timmermann, BM, Schwendeman, A, Cohen, MS
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6861672/
https://ncbi.nlm.nih.gov/pubmed/31371177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2019.06.010
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