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Synthetic high-density lipoprotein nanodisks for targeted withalongolide delivery to adrenocortical carcinoma

Adrenocortical carcinoma (ACC) is a rare endocrine malignancy and has a 5-year survival rate of <35%. ACC cells require cholesterol for steroid hormone production, and this requirement is met via expression on the cell surface of a high level of SRB1, responsible for the uptake of high-density li...

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Detalles Bibliográficos
Publicado en:Int J Nanomedicine
Main Authors: Kuai, Rui, Subramanian, Chitra, White, Peter T, Timmermann, Barbara N, Moon, James J, Cohen, Mark S, Schwendeman, Anna
Formato: Artigo
Idioma:Inglês
Publicado: Dove Medical Press 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5593402/
https://ncbi.nlm.nih.gov/pubmed/28919755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S140591
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