Peptide-Targeted Polyplexes for Aerosol-Mediated Gene Delivery to CD49f-Overexpressing Tumor Lesions in Lung

Peptide ligands can enhance delivery of nucleic acid-loaded nanoparticles to tumors by promoting their cell binding and internalization. Lung tumor lesions accessible from the alveolar side can be transfected, in principle, using gene vectors delivered as an aerosol. The cell surface marker CD49f (I...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Ther Nucleic Acids
Prif Awduron: Taschauer, Alexander, Polzer, Wolfram, Alioglu, Fatih, Billerhart, Magdalena, Decker, Simon, Kittelmann, Theresa, Geppl, Emanuela, Elmenofi, Salma, Zehl, Martin, Urban, Ernst, Sami, Haider, Ogris, Manfred
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Gene & Cell Therapy 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6861568/
https://ncbi.nlm.nih.gov/pubmed/31734558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2019.10.009
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