A sulfonamide sialoside analog for targeting Siglec-8 and -F on immune cells

The Siglec family of cell surface receptors have emerged as attractive targets for cell directed therapies due to their restricted expression on immune cells, endocytic properties and ability to modulate receptor signaling. Human Siglec-8, for instance has been identified as a therapeutic target for...

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Veröffentlicht in:J Am Chem Soc
Hauptverfasser: Nycholat, Corwin M., Duan, Shiteng, Knuplez, Eva, Worth, Charli, Elich, Mila, Yao, Anzhi, O’Sullivan, Jeremy, McBride, Ryan, Wei, Yadong, Fernandes, Steve M., Zhu, Zhou, Schnaar, Ronald L., Bochner, Bruce S., Paulson, James C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6861165/
https://ncbi.nlm.nih.gov/pubmed/31460762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b05769
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