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On-Chip Synthesis and Screening of a Sialoside Library Yields a High Affinity Ligand for Siglec-7
The Siglec family of sialic acid-binding proteins are differentially expressed on white blood cells of the immune system and represent an attractive class of targets for cell-directed therapy. Nanoparticles decorated with high-affinity Siglec ligands show promise for delivering cargo to Siglec-beari...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3751994/ https://ncbi.nlm.nih.gov/pubmed/23597400 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb400125w |
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