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On-Chip Synthesis and Screening of a Sialoside Library Yields a High Affinity Ligand for Siglec-7

The Siglec family of sialic acid-binding proteins are differentially expressed on white blood cells of the immune system and represent an attractive class of targets for cell-directed therapy. Nanoparticles decorated with high-affinity Siglec ligands show promise for delivering cargo to Siglec-beari...

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Hlavní autoři: Rillahan, Cory D., Schwartz, Erik, Rademacher, Christoph, McBride, Ryan, Rangarajan, Janani, Fokin, Valery V., Paulson, James C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3751994/
https://ncbi.nlm.nih.gov/pubmed/23597400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb400125w
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