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Deficiency of C3a receptor attenuates the development of diabetic nephropathy

OBJECTIVE: Diabetic nephropathy (DN) is the leading cause of chronic kidney disease and end-stage renal disease. Emerging evidence suggests that complement activation is involved in the pathogenesis of DN. The aim of this study was to investigate the pathogenic role of C3a and C3a receptor (C3aR) in...

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Bibliografske podrobnosti
izdano v:BMJ Open Diabetes Res Care
Main Authors: Li, Xiao-Qian, Chang, Dong-Yuan, Chen, Min, Zhao, Ming-Hui
Format: Artigo
Jezik:Inglês
Izdano: BMJ Publishing Group 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6861086/
https://ncbi.nlm.nih.gov/pubmed/31798904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjdrc-2019-000817
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