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Deficiency of C3a receptor attenuates the development of diabetic nephropathy

OBJECTIVE: Diabetic nephropathy (DN) is the leading cause of chronic kidney disease and end-stage renal disease. Emerging evidence suggests that complement activation is involved in the pathogenesis of DN. The aim of this study was to investigate the pathogenic role of C3a and C3a receptor (C3aR) in...

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Podrobná bibliografie
Vydáno v:BMJ Open Diabetes Res Care
Hlavní autoři: Li, Xiao-Qian, Chang, Dong-Yuan, Chen, Min, Zhao, Ming-Hui
Médium: Artigo
Jazyk:Inglês
Vydáno: BMJ Publishing Group 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6861086/
https://ncbi.nlm.nih.gov/pubmed/31798904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjdrc-2019-000817
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