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Deficiency of C3a receptor attenuates the development of diabetic nephropathy

OBJECTIVE: Diabetic nephropathy (DN) is the leading cause of chronic kidney disease and end-stage renal disease. Emerging evidence suggests that complement activation is involved in the pathogenesis of DN. The aim of this study was to investigate the pathogenic role of C3a and C3a receptor (C3aR) in...

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Detalhes bibliográficos
Publicado no:BMJ Open Diabetes Res Care
Main Authors: Li, Xiao-Qian, Chang, Dong-Yuan, Chen, Min, Zhao, Ming-Hui
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6861086/
https://ncbi.nlm.nih.gov/pubmed/31798904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjdrc-2019-000817
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