The multifaceted anti-cancer effects of BRAF-inhibitors

The BRAF gene is commonly involved in normal processes of cell growth and differentiation. The BRAF (V600E) mutation is found in several human cancer, causing an increase of cell proliferation due to a modification of the ERK/MAPK-signal cascade. In particular, BRAFV600E mutation is found in those m...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Croce, Laura, Coperchini, Francesca, Magri, Flavia, Chiovato, Luca, Rotondi, Mario
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2019
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6859927/
https://ncbi.nlm.nih.gov/pubmed/31762942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27304
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