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The anti-cancer effects of phenformin in thyroid cancer cell lines and in normal thyrocytes

Phenformin is a biguanide drug which, besides the original anti-diabetic effect, also exerts anti-cancer effects. The aim of this study was to further characterize these latter in terms of both cell-viability and modulation of the secretion of the pro-tumorigenic chemokine CXCL8. Normal human thyroc...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Coperchini, Francesca, Croce, Laura, Denegri, Marco, Awwad, Oriana, Ngnitejeu, Samuel Tata, Magri, Flavia, Chiovato, Luca, Rotondi, Mario
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6849649/
https://ncbi.nlm.nih.gov/pubmed/31741708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27266
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