Effect of Interferon-γ on the Basal and the TNFα-Stimulated Secretion of CXCL8 in Thyroid Cancer Cell Lines Bearing Either the RET/PTC Rearrangement Or the BRAF V600e Mutation

CXCL8 displays several tumor-promoting effects. Targeting and/or lowering CXCL8 concentrations within the tumor microenvironment would produce a therapeutic benefit. Aim of this study was to test the effect of IFNγ on the basal and TNFα-stimulated secretion of CXCL8 in TCP-1 and BCPAP thyroid cancer...

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Detalhes bibliográficos
Publicado no:Mediators Inflamm
Main Authors: Rotondi, Mario, Coperchini, Francesca, Awwad, Oriana, Pignatti, Patrizia, Di Buduo, Christian A., Abbonante, Vittorio, Magri, Flavia, Balduini, Alessandra, Chiovato, Luca
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4983361/
https://ncbi.nlm.nih.gov/pubmed/27555670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/8512417
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