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Structural aspects of chaperone-mediated peptide loading in the MHC-I antigen presentation pathway

Recognition of foreign and dysregulated antigens by the cellular innate and adaptive immune systems is in large part dependent on the cell surface display of peptide/MHC (pMHC) complexes. The formation of such complexes requires the generation of antigenic peptides, proper folding of MHC molecules,...

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Pubblicato in:Crit Rev Biochem Mol Biol
Autori principali: Natarajan, Kannan, Jiang, Jiansheng, Margulies, David H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6859838/
https://ncbi.nlm.nih.gov/pubmed/31084439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10409238.2019.1610352
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