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Variations in MHC class I antigen presentation and immunopeptidome selection pathways

Major histocompatibility class I (MHC-I) proteins mediate immunosurveillance against pathogens and cancers by presenting antigenic or mutated peptides to antigen receptors of CD8+ T cells and by engaging receptors of natural killer (NK) cells. In humans, MHC-I molecules are highly polymorphic. MHC-I...

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發表在:F1000Res
Main Authors: Zaitouna, Anita J., Kaur, Amanpreet, Raghavan, Malini
格式: Artigo
語言:Inglês
出版: F1000 Research Limited 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7525337/
https://ncbi.nlm.nih.gov/pubmed/33014341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.26935.1
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