The Associations Between Cognitive Prognosis and Kynurenines Are Modified by the Apolipoprotein ε4 Allele Variant in Patients With Dementia

BACKGROUND: The apolipoprotein E ε4 gene variant (APOEε4) confers considerable risk for dementia and affects neuroinflammation, brain metabolism, and synaptic function. The kynurenine pathway (KP) gives rise to neuroactive metabolites, which have inflammatory, redox, and excitotoxic effects in the b...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Int J Tryptophan Res
Asıl Yazarlar: Ervik, Arne Olav, Solvang, Stein-Erik Hafstad, Nordrehaug, Jan Erik, Ueland, Per Magne, Midttun, Øivind, Hildre, Audun, McCann, Adrian, Nygård, Ottar, Aarsland, Dag, Giil, Lasse Melvaer
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: SAGE Publications 2019
Konular:
Original Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6859685/
https://ncbi.nlm.nih.gov/pubmed/31798303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1178646919885637
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller