Assessment of computational methods for the analysis of single-cell ATAC-seq data

BACKGROUND: Recent innovations in single-cell Assay for Transposase Accessible Chromatin using sequencing (scATAC-seq) enable profiling of the epigenetic landscape of thousands of individual cells. scATAC-seq data analysis presents unique methodological challenges. scATAC-seq experiments sample DNA,...

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Udgivet i:Genome Biol
Main Authors: Chen, Huidong, Lareau, Caleb, Andreani, Tommaso, Vinyard, Michael E., Garcia, Sara P., Clement, Kendell, Andrade-Navarro, Miguel A., Buenrostro, Jason D., Pinello, Luca
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6859644/
https://ncbi.nlm.nih.gov/pubmed/31739806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-019-1854-5
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