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Effective concentrations enforced by intrinsically disordered linkers are governed by polymer physics

Many multidomain proteins contain disordered linkers that regulate interdomain contacts, and thus the effective concentrations that govern intramolecular reactions. Effective concentrations are rarely measured experimentally, and therefore little is known about how they relate to linker architecture...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Sørensen, Charlotte S., Kjaergaard, Magnus
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6859346/
https://ncbi.nlm.nih.gov/pubmed/31659043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1904813116
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